Generic name: Glibenclamide
Brand Name: ALIGLIBEN
Composition: Glibenclamide……………………………………………..5mg
Indications:
• Second-line treatment of type-2 diabetes in patients under 60: as monotherapy when metformin is not tolerated or contraindicated.
• Used in combination with metformin when glycemic control is inadequate with metformin alone.
Dosage:
• Initial dose: 2.5 to 5 mg once a day, taken orally with first meal. Dose adjustment: according to blood glucose response, increase by no more than 2.5 mg per week; Maintenance dose: 12.5 to 20 mg ; Maximum dose: 20 mg/day.
Contraindications:
• Allergy to sulfonamides.
• Type I diabetics, juvenile diabetes, ketoacidosis.
• Severe renal or hepatic impairment.
Warning:
• The following situations should be used with caution: weak constitution, high fever, nausea and vomiting, hyperthyroidism.
• It should not be taken by the elderly, pregnant women, and lactating women.
Contraindications:
• May cause diarrhea, nausea, vomiting, headache, stomach pain or discomfort.
• Symptoms due to low blood sugar, including: weakness, dizziness, nausea, increased heart rate, sweating trembling and blurred vision
• Rare and severe cases include jaundice, liver function damage, bone marrow suppression, granulocytopenia, thrombocytopenia, etc.
Dosage form: White tablets.
Expiry date : 24 months from the date of manufacture.
Packaging:
• 10 tablets/blister, 2 blisters/box.
• 10 tablets/blister, 50 blisters/box.
Storage:
• Keep in original packaging in a dark, dry place. (10-30℃).
• Keep out of reach of children.
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