Brand name: ALITRAMETINIB
Composition:
Each tablet contains:
Trametinib dimethyl sulfoxide………………………………2mg
Indications:
• Trametinib is a kinase inhibitor indicated as a single agent for the treatment of BRAF-inhibitor treatment-naive patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations.
Or in combination with dabrafenib:
• To treat unresectable or metastatic melanoma patients with BRAF V600E or V600K mutation positivity.
• For postoperative adjuvant treatment of BRAF V600E or V600K mutation positive melanoma.
• Used to treat metastatic non-small cell lung cancer caused by BRAF V600E mutation.
Dosage:
• Adult patients：2mg orally once daily.
• Pediatric patients：
Body weight 26-37kg：1mg orally once a day.
Body weight 38-50kg：1.5mg orally once a day.
Body weight 51kg and above：2mg orally once daily.
• Take this product at least 1 hour before meals or 2 hours after meals.
• Continue medication, until disease progression or unacceptable toxicity.
Contraindications: None.
Warnings:
• New Primary Malignancies, Cutaneous and Non-Cutaneous.
• Be alert to bleeding events when combined with Dabrafenib and stop taking this product if the situation is serious.
• It may cause venous thromboembolism.
• Cardiomyopathy should be monitored during treatment.
• Embryo-Fetal Toxicity: Can cause fetal harm. Advise females of reproductive potential of potential risk to a fetus and to use effective contraception.
Adverse Effects: Fever, nausea, rash, chills, diarrhea, vomiting, etc.
Dosage form: Yellow tablets.
Expiry date: 24 months from the date of manufacture.
Packaging: 30 tablets/bottle.
Storage:
• Protected from light, sealed in original packaging, and stored at 20℃- 25℃.
• Keep out of reach of children.
DISCLAIMER
The information on this website about our medications is intended for general educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking care because of something you have read on this website.
For your safety:
Do not self-diagnose or treat any medical condition based solely on the information on this website. If you have any questions or concerns about a medication, please talk to your doctor or pharmacist.
