Brand name: ARIMIDEX
Composition:
Each tablet contains:
Anastrozole ……………………………..1mg
Indications:
- It is suitable for advanced breast cancer in postmenopausal women who cannot be controlled by tamoxifen and other anti-estrogen therapies.
- Adjuvant treatment of estrogen-positive early breast cancer in postmenopausal women.
- For patients with negative estrogen receptors and a positive clinical response to tamoxifen, this product may be considered.
Dosage:
- Take 1 tablet (1mg) orally once daily. In patients with mild hepatic impairment or mild to moderate renal impairment, dose adjustment is generally not required
Contraindications:
This product is contraindicated in the following situations:
- Premenopausal women
- Pregnant or lactating women
- Patients with severe renal damage (creatinine clearance <20ml/min)
- Patients with moderate to severe liver damage
- Known Patients who are highly sensitive to anastrozole and its preparation excipients
Warnings:
- There is no data on the safety of anastrozole tablets in patients with moderate to severe hepatic impairment and severe renal impairment.
- When doubts arise about hormone levels, amenorrhea should be considered to be due to a disruption in hormonal balance.
- This product has no significant impact on patients’ ability to drive and operate machinery.
- However, it has been reported that some patients have symptoms of fatigue and depression.
- When the above symptoms persist, patients should pay special attention when driving and operating machinery.
Adverse Effects:
- Side effects of this product mainly include skin flushing, vaginal dryness, excessive hair oil secretion, gastrointestinal disorders (anorexia, nausea, vomiting and diarrhea), fatigue, depression, headache or rash, etc. Side effects are usually mild or moderate and easily tolerated by patients.
- Uterine bleeding with this product is occasionally reported, mainly in the first few weeks after patients switch from existing hormone therapy to this product. If bleeding continues, further evaluation is required.
- Changes in liver function (such as increased transpeptidase and alkaline phosphatase) have been reported in patients with advanced breast cancer treated with this product, but many of these patients already have liver metastasis or bone metastasis. Research into the causes of these changes has not yet been conducted. Clinical observation shows that this product can slightly increase plasma total cholesterol levels.
Dosage form: White tablets.
Expiry date: 24 months after date of manufacture.
Packaging: 1 mg/tablets, 10 tablets/blister, 10 blisters/ box.
Storage:
- Protected from light, sealed, and stored at 20℃- 25℃.
- Keep out of reach of children.
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Do not self-diagnose or treat any medical condition based solely on the information on this website. If you have any questions or concerns about a medication, please talk to your doctor or pharmacist.