ALIDABRAFENIB

COMPOSITION
Dabrafenib mesylate………………………………….75mg
INDICATION

Dabrafenib is a kinase inhibitor indicated. It can be taken alone or in combination with trametinib.

  • Used to treat unresectable or metastatic melanoma patients with BRAF V600E mutation positivity.
  • Used for postoperative adjuvant treatment of BRAF V600E mutation positive melanoma.
  • Used to treat metastatic non-small cell lung cancer caused by BRAF V600E mutation.

PACKAGING:
30 tablets/bottle.

Reg No: 10 L 1222/24
Download ALIDABRAFENIB Drug Registration Certificate

Brand name: ALIDABRAFENIB


Composition:
Each tablet contains:
Dabrafenib mesylate………………………………….75mg


Indications:

Dabrafenib is a kinase inhibitor indicated. It can be taken alone or in combination with trametinib.

  • Used to treat unresectable or metastatic melanoma patients with BRAF V600E mutation positivity.
  • Used for postoperative adjuvant treatment of BRAF V600E mutation positive melanoma.
  • Used to treat metastatic non-small cell lung cancer caused by BRAF V600E mutation.

Dosage:

  • Adult patients: 150mg orally twice daily.
  • Pediatric patients:
    • Body weight 26-37kg:75mg orally twice a day.
    • Body weight 38-50kg:100mg orally twice a day.
    • Body weight 51kg and above:150mg orally twice daily.
  • Take this product at least 1 hour before meals or 2 hours after meals, administration interval of approximately 12 hours.
  • Continue medication, until disease progression or unacceptable toxicity.

Contraindications: None.


Warnings:

  • Monitor patients for newly developed malignant tumors during treatment.
  • In combination with trametinib monitor for signs and symptoms of bleeding.
  • May cause venous thromboembolism during medication.
  • Cardiomyopathy should be monitored during treatment.
  • Embryo-Fetal Toxicity: Can cause fetal harm. Advise females of reproductive potential of potential risk to a fetus and to use effective contraception.

Adverse Effects:
Fever, rash, chills, headache, joint pain, cough, etc.


Dosage form: Red capsule.


Expiry date: 24 months from the date of manufacture.


Packaging: 120 capsules/bottle.


Storage:

  • Protected from light, sealed, and stored at 20℃- 25℃.
  • Keep out of reach of children.

DISCLAIMER

The information on this website about our medications is intended for general educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking care because of something you have read on this website.

For your safety:

Do not self-diagnose or treat any medical condition based solely on the information on this website. If you have any questions or concerns about a medication, please talk to your doctor or pharmacist.