Brand name: ALIDABRAFENIB
Composition:
Each tablet contains:
Dabrafenib mesylate………………………………….75mg
Indications:
Dabrafenib is a kinase inhibitor indicated. It can be taken alone or in combination with trametinib.
- Used to treat unresectable or metastatic melanoma patients with BRAF V600E mutation positivity.
- Used for postoperative adjuvant treatment of BRAF V600E mutation positive melanoma.
- Used to treat metastatic non-small cell lung cancer caused by BRAF V600E mutation.
Dosage:
- Adult patients: 150mg orally twice daily.
- Pediatric patients:
- Body weight 26-37kg:75mg orally twice a day.
- Body weight 38-50kg:100mg orally twice a day.
- Body weight 51kg and above:150mg orally twice daily.
- Take this product at least 1 hour before meals or 2 hours after meals, administration interval of approximately 12 hours.
- Continue medication, until disease progression or unacceptable toxicity.
Contraindications: None.
Warnings:
- Monitor patients for newly developed malignant tumors during treatment.
- In combination with trametinib monitor for signs and symptoms of bleeding.
- May cause venous thromboembolism during medication.
- Cardiomyopathy should be monitored during treatment.
- Embryo-Fetal Toxicity: Can cause fetal harm. Advise females of reproductive potential of potential risk to a fetus and to use effective contraception.
Adverse Effects:
Fever, rash, chills, headache, joint pain, cough, etc.
Dosage form: Red capsule.
Expiry date: 24 months from the date of manufacture.
Packaging: 120 capsules/bottle.
Storage:
- Protected from light, sealed, and stored at 20℃- 25℃.
- Keep out of reach of children.
DISCLAIMER
The information on this website about our medications is intended for general educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking care because of something you have read on this website.
For your safety:
Do not self-diagnose or treat any medical condition based solely on the information on this website. If you have any questions or concerns about a medication, please talk to your doctor or pharmacist.